When you can't breathe, you can't scream!
“A slick, scary, funny creature feature…” – Roger Ebert, Chicago Sun-Times
Starring: Jennifer Lopez, Ice Cube, Jon Voight
A documentary film crew headed by anthropologist Steve Cale (Eric Stoltz) and director Terri Flores (Jennifer Lopez) travel down the Amazon River in search of a mysterious Indian tribe. On their journey they save a man, Paul Sarone (Jon Voight), from a sinking boat. He offers to help in their search for the tribe, but he is actually a snake-hunter looking for the legendary Anaconda snake. When an accident leaves Cale unconcious, Sarone takes charge of the boat, leaving the rest of the crew in grave danger.